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Index > Protein center > Abcg2(Gene name) > Mouse
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  • Abcg2 (Gene name),
  • ATP-binding cassette sub-family G member 2 (Protein name ),  ABCG2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Abcg2(Abcp;Bcrp1);
    Protein name:
    ATP-binding cassette sub-family G member 2;
    Alternative:
    Urate exporter;Breast cancer resistance protein 1 homolog;
    CD:
    CD338;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Monomer or homodimer; disulfide-linked.
    Function:
    Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux (By similarity). May play a role in early stem cell self-renewal by blocking differentiation.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    657
    Sequence:
    50:
    MSSSNDHVLV | PMSQRNNNGL | PRTNSRAVRT | LAEGDVLSFH | HITYRVKVKS | 
    100:
    GFLVRKTVEK | EILSDINGIM | KPGLNAILGP | TGGGKSSLLD | VLAARKDPKG | 
    150:
    LSGDVLINGA | PQPAHFKCCS | GYVVQDDVVM | GTLTVRENLQ | FSAALRLPTT | 
    200:
    MKNHEKNERI | NTIIKELGLE | KVADSKVGTQ | FIRGISGGER | KRTSIGMELI | 
    250:
    TDPSILFLDE | PTTGLDSSTA | NAVLLLLKRM | SKQGRTIIFS | IHQPRYSIFK | 
    300:
    LFDSLTLLAS | GKLVFHGPAQ | KALEYFASAG | YHCEPYNNPA | DFFLDVINGD | 
    350:
    SSAVMLNREE | QDNEANKTEE | PSKGEKPVIE | NLSEFYINSA | IYGETKAELD | 
    400:
    QLPGAQEKKG | TSAFKEPVYV | TSFCHQLRWI | ARRSFKNLLG | NPQASVAQLI | 
    450:
    VTVILGLIIG | AIYFDLKYDA | AGMQNRAGVL | FFLTTNQCFS | SVSAVELFVV | 
    500:
    EKKLFIHEYI | SGYYRVSSYF | FGKVMSDLLP | MRFLPSVIFT | CVLYFMLGLK | 
    550:
    KTVDAFFIMM | FTLIMVAYTA | SSMALAIATG | QSVVSVATLL | MTIAFVFMML | 
    600:
    FSGLLVNLRT | IGPWLSWLQY | FSIPRYGFTA | LQYNEFLGQE | FCPGFNVTDN | 
    650:
    STCVNSYAIC | TGNEYLINQG | IELSPWGLWK | NHVALACMII | IFLTIAYLKL | 
    657:
    LFLKKYS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    SMR:
    String:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse ATP-binding cassette sub-family G member 2
    Cat.:
    E0960h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse ATP-binding cassette sub-family G member 2
    Cat.:
    E0960b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse ATP-binding cassette sub-family G member 2
    Cat.:
    E0960m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse ATP-binding cassette sub-family G member 2
    Cat.:
    E0960p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse ATP-binding cassette sub-family G member 2
    Cat.:
    E0960r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse ATP-binding cassette sub-family G member 2
    Cat.:
    U0960r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse ATP-binding cassette sub-family G member 2
    Cat.:
    U0960b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse ATP-binding cassette sub-family G member 2
    Cat.:
    U0960p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse ATP-binding cassette sub-family G member 2
    Cat.:
    U0960h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse ATP-binding cassette sub-family G member 2
    Cat.:
    U0960m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse ATP-binding cassette sub-family G member 2
    Polyclonal Antibody for Mouse ATP-binding cassette sub-family G member 2
    Cat.:
    P0960Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse ATP-binding cassette sub-family G member 2
    Cat.:
    P0960Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse ATP-binding cassette sub-family G member 2
    Cat.:
    P0960Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse ATP-binding cassette sub-family G member 2
    Monoclonal Antibody for Mouse ATP-binding cassette sub-family G member 2
    Monoclonal Antibody for Mouse ATP-binding cassette sub-family G member 2
    Monoclonal Antibody for Mouse ATP-binding cassette sub-family G member 2
    Monoclonal Antibody for Mouse ATP-binding cassette sub-family G member 2
    Monoclonal Antibody for Mouse ATP-binding cassette sub-family G member 2
    Protein for Mouse ATP-binding cassette sub-family G member 2
    Protein for Mouse ATP-binding cassette sub-family G member 2
    Protein for Mouse ATP-binding cassette sub-family G member 2
    Protein for Mouse ATP-binding cassette sub-family G member 2
    Protein for Mouse ATP-binding cassette sub-family G member 2

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The mouse Bcrp1/Mxr/Abcp gene: amplification and overexpression in cell lines selected for resistance to topotecan, mitoxantrone, or doxorubicin."
      Allen J.D. , Brinkhuis R.F. , Wijnholds J. , Schinkel A.H.
      Cancer Res.59:4237-4241(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION
      strain: FVB.
      tissue: Liver.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6NCr.
      tissue: Hematopoietic stem cell.
    3. 3.
      "A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance."
      Allikmets R. , Schriml L.M. , Hutchinson A. , Romano-Spica V. , Dean M.
      Cancer Res.58:5337-5339(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 511-657
      strain: C57BL/6J.
      tissue: Placenta.
    4. 4.
      "Role of breast cancer resistance protein in the bioavailability and fetal penetration of topotecan."
      Jonker J.W. , Smit J.W. , Brinkhuis R.F. , Maliepaard M. , Beijnen J.H. , Schellens J.H. , Schinkel A.H.
      J. Natl. Cancer Inst.92:1651-1656(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    5. 5.
      "The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype."
      Zhou S. , Schuetz J.D. , Bunting K.D. , Colapietro A.M. , Sampath J. , Morris J.J. , Lagutina I. , Grosveld G.C. , Osawa M. , Nakauchi H. , Sorrentino B.P.
      Nat. Med.7:1028-1034(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
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